Transmission of L. carinii to Laboratory Animals

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Natural transmission of Pneumocystis carinii in nonimmunosuppressed animals: early contagiousness of experimentally infected rabbits (Oryctolagus cuniculus).

Airborne transmission of Pneumocystis carinii has been established, but the infective form and the sources of infection remain unknown. Animal models for studies of P. carinii have previously been limited to immunosuppressed rodents; however, this study was performed with nonimmunodepressed P. carinii-free rabbits. This study was aimed at determining (i) the delay between inoculation of animals...

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Laboratory investigation of Pneumocystis carinii pneumonia.

Introduction Unexpected Pneumocystis carinii pneumonia (PCP) led to the identification of the acquired immunodeficiency syndrome (AIDS). The laboratory diagnosis ofP carinii infection has had a less auspicious start. As this fungus is not easily grown, there has been a tendency for physicians to make a clinical diagnosis. Early and rapid confirmation ofthe diagnosis ofPCP is important and the d...

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Transmission of Pneumocystis carinii from patients to hospital staff.

BACKGROUND An extrahuman reservoir of human pathogenic Pneumocystis carinii remains unknown. Host to host transmission has been described in animal studies and in cluster cases among immunodeficient patients. P carinii DNA has recently been detected in air filters from inpatient and outpatient rooms in departments of infectious diseases managing patients with P carinii pneumonia (PCP), suggesti...

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ژورنال

عنوان ژورنال: Nature

سال: 1946

ISSN: 0028-0836,1476-4687

DOI: 10.1038/158418a0